World No 3 Carlos Alcaraz hopes to be fit for must-win clash against Andrey Rublev (from 1pm GMT)
Two-time former season-ending champion Alexander Zverev takes on Casper Ruud (not before 7.30pm)
Alcaraz’s participation in Turin has been cast into doubt after he pulled out of practice with illness.
His coach Juan Carlos Ferrero told Spanish media the 21-year-old cut short his session after just five minutes as a chest complaint was making breathing difficult.
But suggesting Alcaraz would nonetheless he ready to play despite not feeling completely fit, Ferrera was quoted as saying by Reuters: “As soon as he moves a little, it’s hard for him to breathe. His chest is a bit tight. It’s a bad time to get sick.
“We should not anticipate whether or not he will play [on Wednesday]. We have all played in these circumstances. I don’t think he’s going to be so bad that he won’t be able to play. It’s going to be difficult for him to be 100 per cent.
“Rublev is a player who moves a lot, you have to be very good on your legs and, right now, that’s what’s costing him a little more, recovering between points.”
Britain’s Henry Patten and partner Harri Helioevaara are on the brink of the doubles semi-finals after a second straight win, beating Australians Max Purcell and Jordan Thompson 7-6 7-5 in a repeat of their Wimbledon final.